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The goal of the Molecular Targeting area is to understand the molecular and cellular mechanisms involved in several processes affecting diseases in order to unveil and characterize new targets for pathologies, focusing on brain related disorders and cancer.
Strategies to generate and/or improve therapeutic drugs require a better comprehension of the molecular mechanisms to identify putative targets. Therefore, the area focuses on the molecular mechanisms controlling several fundamental cellular processes such as post-translational modifications, signal transduction and degradation pathways.
In order to achieve these goals a wide range of experimental models (cell clones, animal models and patient samples) are used, in combination with state-of-the-art molecular and cellular biology tools, for identifying new targets.