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Dra. Ana Clara Liberman

aliberman@ibioba-mpsp-conicet.gov.ar

Bioquímica de la Facultad de Farmacia y Bioquímica de la Universidad de Buenos Aires. Doctorado en la Facultad de Ciencias Exactas y Naturales de la Universidad de Buenos Aires (2007). Postdoctorado en la Facultad de Ciencias Exactas y Naturales de la Universidad de Buenos Aires (2007- 2009). Investigadora Asistente en el Laboratorio de Fisiología y Biología Molecular, FCEN- UBA (2009-2012). Lider de Proyecto en "Efectos de los glucocorticoides en células inmunes" y "Señalización por P2RX7 en el SNC y participación de PARP-1" en el IBioBA-MPSP desde 2012, con categoría de Investigadora Adjunta de CONICET desde 2014.

Publicaciones destacadas


Antunica-Noguerol, M., Budziñski, ML., Druker, J., Gassen, NC., Sokn, MC., Senin, S., Aprile-Garcia, F., Holsboer, F., Rein, T., Liberman, AC., Arzt, E.
The activity of the glucocorticoid receptor is regulated by SUMO conjugation to FKBP51
Cell Death Differ. 23:1579-91 (2016)


Druker, J.; Liberman, A.C.; Antunica Noguerol, M.; Gerez, J.; Paez Pereda, M.; Rein, T.; Iñiguez Lluhí, J.A.; Holsboer, F., Arzt, E.
RSUME enhances Glucocorticoid Receptor SUMOylation and transcriptional activity
Molecular and Cellular Biology 33:2116-27 (2013)


Liberman, A., Antunica Noguerol, M., Ferraz, V., Palermo Neto, J., Castro, C., Druker, J., Holsboer, F., Gerlo, S., De Bosscher, K., Haegeman, G., Arzt, E.
Compound A, a dissociated glucocorticoid receptor modulator, inhibits T-bet and induces GATA-3 activity in T cells.
PLoS One 7:e35155 (2012)


Liberman, A., Refojo, D., Antunica Noguerol, M., Holsboer, F., Arzt, E.
Underlying mechanisms of cAMP- and glucocorticoid-mediated inhibition of FasL expression in activation-induced cell death.
Molecular Immunology. 50:220-35 (2012)


Liberman AC, Castro CN, Barcala Tabarrozzi A, Druker J, Antunica Noguerol M, Perone MJ Arzt E.
Molecular mechanisms of glucocorticoids action: from basic research to clinical implications
Current Immunology Reviews 6:371-380 (2010)


Liberman AC, Castro CN., Noguerol MA, Barcala Tabarrozi AE, Druker J, Perone MJ, Arzt E.
Immunomodulation by glucocorticoids: from basic research to clinical implications.
Current Immunol Reviews 12:122-127 (2010)


Liberman AC, Druker J, Refojo D, Holsboer F., Arzt E.
Glucocorticoids inhibit GATA-3 phosphorylation and activity in T cells
FASEB J. 23:1558-71 (2009)


Liberman AC, Druker J, Garcia FA, Holsboer F, Arzt E.
Intracellular molecular signaling. Basis for specificity to glucocorticoid anti-inflammatory actions
Ann N Y Acad Sci. 1153:6-13 (2009)


Liberman AC, Refojo D, Druker J, Toscano MA, Rhein T, Holsboer F., Arzt E.
The activated glucocorticoid receptor inhibits the transcription factor T-bet by direct protein-protein interaction
FASEB J. 21:1177-88 (2007)


Liberman AC, Druker J, Perone M, Holsboer F., Arzt E.
Glucocorticoids in the regulation of transcription factors that control cytokine synthesis.
Cytokine Growth Factor Rev. 18:45-56 (2007)


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