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Dr. Marcelo J. Perone

mperone@ibioba-mpsp-conicet.gov.ar

Graduado en Química y Bioquímica y Doctorado en Bioquímica de la Facultad de Ciencias Exactas de la Universidad de La Plata. Postdoctorado en las Universidades de Gales y Manchester (Gran Bretaña) y en las Universidades de Pittsburgh y en la UCLA (Estados Unidos).
Investigador del CONICET. Actualmente a cargo del grupo de investigación "Diabetes / Inmunología" en el IBioBA-MPSP.

Publicaciones destacadas


Gimeno ML, Fuertes F, Barcala Tabarrozzi AE, Attorressi AI, Cucchiani R, Corrales L, Oliveira TC, Sogayar MC, Labriola L, Dewey RA, Perone MJ.
Pluripotent Nontumorigenic Adipose Tissue-Derived Muse Cells Have Immunomodulatory Capacity Mediated by Transforming Growth Factor-β1
Stem Cells TranslationalMedicine 6:161-173 (2017)


Fisch SC, Gimeno ML, Phan JD, Simerman AA, Dumesic DA, Perone MJ and Chazenbalk GD.
Pluripotent non-tumorigenic multilineage differentiating stress enduring cells (Muse cells): a seven-year Retrospective
Stem Cell Research & Therapy 8:227 (2017)


Barcala Tabarrozzi AE, Andreone L, Deckers J, Castro CN, Gimeno ML, Ariolfo L, Berguer PM, Antunica Noguerol M, Liberman AC, Vettorazzi S, Tuckermann JP, De Bosscher K, Perone MJ
GR-independent down-modulation on GM-CSF bone marrow-derived dendritic cells by the selective glucocorticoid receptor modulator Compound A
Sci. Rep. 6, 36646 (2016)


Rodríguez TM, Saldías A, Irigo M, Velasco Zamora J, Perone MJ, Dewey RA.
Effect of TGF-ß1 stimulation on the secretome of human adipose-derived mesenchymal stromal cells
Stem Cells Transl Med. 4:894-898 (2015)


Castro CN, Barcala Tabarrozzi AE, Winnewisser J, Gimeno ML, Antunica Noguerol M, Liberman AC, Paz DA, Dewey RA, Perone MJ
Curcumin ameliorates autoimmune diabetes. Evidence in accelerated murine models of type 1 diabetes.
Clin Exp Immunol. 177:149-60 (2014)


Simerman AA, Perone MJ, Gimeno ML, Dumesic DA and Chazenbalk GD
A Mystery Unraveled: Non-tumorigenic pluripotent stem cells in human adult tissues
Expert Opinion on Biological Therapy 14:917-929 (2014)


Barcala Tabarrozzi, A.E.; Castro, C.N.; Dewey, R.A.; Sogayar, M.C.; Labriola, L.; Perone, M.J.
Therapeutics utilizing cell-based interventions for type 1 diabetes mellitus
Clinical & Experimental Immunology 171:135-146 (2013)


Castro CN, Barcala Tabarrozi AE, Antunica Noguerol M, Liberman AC, Dewey RA, Arzt E, Morelli AE, Perone MJ.
Disease-modifying immunotherapy for the management of autoimmune diabetes
Neuroimmunomodulation 17:173-176 (2010)


Liberman AC, Castro CN, Barcala Tabarrozzi A, Druker J, Antunica Noguerol M, Perone MJ Arzt E.
Molecular mechanisms of glucocorticoids action: from basic research to clinical implications
Current Immunology Reviews 6:371-380 (2010)


Perone MJ, Bertera S, Shufesky WJ, Divito SJ, Montecalvo A, Mathers AR, Larregina AT, Pang M, Seth N, Wucherpfennig KW, Trucco M, Baum LG, Morelli AE.
Suppression of autoimmune diabetes by soluble galectin-1
The Journal of Immunology 182:2641-2653 (2009)


Schaaf C, Shan B, Buchfelder M, Losa M, Kreutzer J, Rachinger W, Stalla GK, Schilling T, Arzt E, Perone MJ, Renner U.
Curcumin acts as anti-tumorigenic and hormone-suppressive agent in murine and human pituitary tumour cells in vitro and in vivo
Endocrine-Related Cancer 16:1339-1350 (2009)


Liberman AC, Druker J, Perone MJ, Arzt E.
Glucocorticoids in the regulation of transcription factors that control cytokine synthesis
Cytokine and Growth Factor Reviews 18:45-56 (2007)


Wang Z, Larregina AT, Shufesky WJ, Perone MJ, Zahorchak AF, Thomson AW, Morelli AE.
Use of the inhibitory effect of apoptotic cells on dendritic cells for graft survival via T cell deletion and regulatory T cells
American Journal of Transplantation 6:1297-1311 (2006)


Perone MJ, Larregina AT, Shufesky WJ, Papworth GD, Sullivan MLG, Zahorchak AF, Stolz DB, Baum LG, Watkins SC, Thomson AW, Morelli AE.
Transgenic galectin-1 induces maturation of dendritic cells that elicit contrasting responses on naïve and activated T cells
The Journal of Immunology 176:7207-7220 (2006)


Perone MJ, Bertera S, Shufesky WJ, Zahorchak A, Piganelli J, Baum LG, Trucco M, Morelli AE.
Dendritic cells expressing transgenic galectin-1 delay onset of autoimmune diabetes in mice
The Journal of Immunology 177:5278-5289 (2006)


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