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List of Recent Publications

Petrungaro G, Uriu K, and Morelli LG.
Mobility-induced persistent chimera states
Phys. Rev. E 96, 062210 (2018)

Koile, D; Cordoba, M; de Sousa Serro, M; Kauffman, M; Yankilevich, P.
GenIO: a phenotype-genotype analysis web server for clinical genomics of rare diseases
BMC Bioinformatics 19:25 (2018)

Andreone L, Gimeno ML and Perone MJ
Interactions Between the Neuroendocrine System and T Lymphocytes in Diabetes
Front. Endocrinol. 9:229 (2018)

Fuertes M., Sapochnik M., Tedesco L., Senin S., Attorresi A., Ajler P., Carrizo G., Cervio A., Sevlever G., Bonfiglio JJ., Stalla GK., Arzt E.
Protein stabilization by RSUME accounts for PTTG pituitary tumor abundance and oncogenicity
Endocr Relat Cancer 25:665-676 (2018)

Dedic N, Kühne C, Jakovcevski M, Hartmann J, Genewsky A, Gomes KS, Anderzhanova E, Pöhlmann M, Chang S, Kolarz A, Vogl AM, Metzger MW, Schmid B, Almada RC, Ressler KJ, Wotjak CT, Grinevich V, Chen A, Schmidt MV, Wurst W, Refojo D, Deussing JM.
CRH acts anxiolytic by modulating dopamine release through a subset of GABAergic long-range projection neurons
Nat Neurosci 21:803-807 (2018)

Jörg DJ, Morelli LG, Jülicher F
Chemical event chain model of coupled genetic oscillators
Phys Rev E. 97:032409 (2018)

Bollini M, Leal ES, Adler NS, Aucar MG, Fernández GA, Pascual MJ, Merwaiss F, Alvarez DE, Cavasotto CN
Discovery of Novel Bovine Viral Diarrhea Inhibitors Using Structure-Based Virtual Screening on the Envelope Protein E2
Front Chem 6:79 (2018)

Tomasella E, Bechelli L, Ogando MB, Mininni C, Di Guilmi MN, De Fino F, Zanutto S, Elgoyhen AB, Marin-Burgin A, Gelman DM
Deletion of dopamine D2 receptors from parvalbumin interneurons in mouse causes schizophrenia-like phenotypes
Proc Natl Acad Sci 115:3476-3481 (2018)

Ruiz MS, Sanchez MB, Gutiérrez L, Koile D, Yankilevich P, Mosqueira C, Cranco S, Custidiano MDR, Freitas J, Foncuberta C, Moiraghi B, Pavlovsky C, Pérez MA, Ventriglia V, Ávalos JS, Mordoh J, Larripa I, Bianchini M
Evaluation of the primitive fraction by functional in vitro assays at the RNA and DNA level represents a novel tool for complementing molecular monitoring in chronic myeloid leukemia
Oncotarget 9:20255-20264 (2018)

Lleras Forero L, Narayanan R, Huitema LF, VanBergen M, Apschner A, Peterson-Maduro J, Logister I, Valentin G, Morelli LG, Oates AC, Schulte-Merker S
Segmentation of the zebrafish axial skeleton relies on notochord sheath cells and not on the segmentation clock
Elife 7 (2018)

Liberman AC, Budziñski ML, Sokn C, Gobbini RP, Steininger A, Arzt E
Regulatory and Mechanistic Actions of Glucocorticoids on T and Inflammatory Cells
Front Endocrinol 9:235 (2018)

Surkin PN, Brenhouse H, Deak T, Liberman AC, Lasaga M
Stress, alcohol and infection during early development: a brief review of common outcomes and mechanisms
J Neuroendocrinol e12602 (2018)

Aris M, Bravo AI, Pampena MB, Blanco PA, Carri I, Koile D, Yankilevich P, Levy EM, Barrio MM, Mordoh J
Changes in the TCRβ Repertoire and Tumor Immune Signature From a Cutaneous Melanoma Patient Immunized With the CSF-470 Vaccine: A Case Report
Front Immunol 9:955 (2018)

Cavasotto CN, Adler NS, Aucar MG
Quantum Chemical Approaches in Structure-Based Virtual Screening and Lead Optimization
Front Chem 6:188 (2018)

Petersen H, Mostafa A, Tantawy MA, Iqbal AA, Hoffmann D, Tallam A, Selvakumar B, Pessler F, Beer M, Rautenschlein S, Pleschka S
NS Segment of a 1918 Influenza A Virus-Descendent Enhances Replication of H1N1pdm09 and Virus-Induced Cellular Immune Response in Mammalian and Avian Systems
Front Microbiol 9:526 (2018)

Leroux AE, Schulze JO, Biondi RM
AGC kinases, mechanisms of regulation ‎and innovative drug development
Semin Cancer Biol. 48:1-17 (2018)

Pleli T, Mondorf A, Ferreiros N, Thomas D, Dvorak K, Biondi RM, Heringdorf DMZ, Zeuzem S, Geisslinger G, Zimmermann H, Waidmann O, Piiper A.
Activation of Adenylyl Cyclase Causes Stimulation of Adenosine Receptors
Cell Physiol Biochem. 45:2516-2528 (2018)

Deussing JM, Arzt E
P2X7 Receptor: A Potential Therapeutic Target for Depression?
Trends Mol Med. 24:736-747 (2018)

Gimeno ML, Fuertes F, Barcala Tabarrozzi AE, Attorressi AI, Cucchiani R, Corrales L, Oliveira TC, Sogayar MC, Labriola L, Dewey RA, Perone MJ.
Pluripotent Nontumorigenic Adipose Tissue-Derived Muse Cells Have Immunomodulatory Capacity Mediated by Transforming Growth Factor-β1
Stem Cells TranslationalMedicine 6:161-173 (2017)

Metzger MW, Walser SM, Aprile-Garcia F, Dedic N, Chen A, Holsboer F, Arzt E, Wurst W, Deussing JM
Genetically dissecting P2rx7 expression within the central nervous system using conditional humanized mice
Purinergic Signal. 13:153-170 (2017)

Sapochnik M, Haedo MR, Fuertes M, Ajler P, Carrizo G, Cervio A, Sevlever G, Stalla GK, Arzt E.
Autocrine IL-6 mediates pituitary tumor senescence
Oncotarget 8:4690-4702 (2017)

Lia Frenkel, Nara I. Muraro, Andrea N. Beltrán González, María S. Marcora, Guillermo Bernabó, Christiane Hermann-Luibl, Juan I. Romero, Charlotte Helfrich-Förster, Eduardo M. Castaño, Cristina Marino-Busjle, Daniel J. Calvo, M. Fernanda Ceriani.
Organization of Circadian Behavior Relies on Glycinergic Transmission
Cell Reports 19:72–85 (2017)

Iván M. Lengyel and Luis G. Morelli
Multiple binding sites for transcriptional repressors can produce regular bursting and enhance noise suppression
Phys. Rev. E 95, 042412 (2017)

Inda C, Bonfiglio JJ, Dos Santos Claro PA, Senin SA, Armando NG, Deussing JM, Silberstein S
cAMP-dependent cell differentiation triggered by activated CRHR1 in hippocampal neuronal cells
Sci Rep. 7:1944. (2017)

Leal ES, Aucar MG, Gebhard LG, Iglesias NG, Pascual MJ, Casal JJ, Gamarnik AV, Cavasotto CN, Bollini M.
Discovery of novel Dengue virus entry inhibitors via a structure-based approach
Bioorg Med Chem Lett. 27:3851-3855 (2017)

Romano SA, Pérez-Schuster V, Jouary A, Boulanger-Weill J, Candeo A, Pietri T, Sumbre G.
An integrated calcium imaging processing toolbox for the analysis of neuronal population dynamics
PLoS Comput Biol 13:e1005526 (2017)

Romano SA, Pérez-Schuster V, Sumbre G,
Functional Interactions between Newborn and Mature Neurons Leading to Integration into Established Neuronal Circuits
Current Biology 27:1-14 (2017)

Pietri T, Romano SA, Pérez-Schuster V, Boulanger-Weill J, Candat V, Sumbre G.
The Emergence of the Spatial Structure of Tectal Spontaneous Activity Is Independent of Visual Inputs
Cell Reports 19:939–948 (2017)

Inda C, Armando NG, Dos Santos Claro PA, Silberstein S.
Endocrinology and the brain: corticotropin-releasing hormone signaling
Endocr Connect 6:R99-R120 (2017)

Pozo Devoto V, Dimopoulos N, Alloatti M, Pardi MB, Saez T, Otero M,Cromberg L, Marin-Burgin A, Scassa E., Stokin G, Schinder A, Sevlever G, Falzone T
αSynuclein control of mitochondrial homeostasis in human-derived neurons is disrupted by mutations leading to Parkinson’s Disease
Scientific Reports 7:5042 (2017)

Fisch SC, Gimeno ML, Phan JD, Simerman AA, Dumesic DA, Perone MJ and Chazenbalk GD.
Pluripotent non-tumorigenic multilineage differentiating stress enduring cells (Muse cells): a seven-year Retrospective
Stem Cell Research & Therapy 8:227 (2017)

Renner U, Sapochnik M, Lucia K, Stalla GK, Arzt E.
Intrahypophyseal Immune-Endocrine Interactions: Endocrine Integration of the Inflammatory Inputs
Front Horm Res. Basel 48:37-47 (2017)

Sapochnik M, Fuertes M, Arzt E.
Programmed cell senescence: role of IL-6 in the pituitary
J Mol Endocrinol 58:R241-R253 (2017)

Metzger MW, Walser SM, Dedic N, Aprile-Garcia F, Jakubcakova V, Adamczyk M, Webb KJ, Uhr M, Refojo D, Schmidt MV, Friess E, Steiger A, Kimura M, Chen A, Holsboer F, Arzt E, Wurst W, Deussing JM.
Heterozygosity for the Mood Disorder-Associated Variant Gln460Arg Alters P2X7 Receptor Function and Sleep Quality
J Neurosci. 3748:11688-11700 (2017)

Barabas FM, Masullo LA, Bordenave MD, Giusti S, Unsain N, Refojo D, Cáceres A, Stefani FD.
Automated quantification of protein periodic nanostructures in fluorescence nanoscopy images: abundance and regularity of neuronal spectrin membrane-associated skeleton
Sci Rep. 7:16029 (2017)

Arencibia JM, Fröhner W, Krupa M, Pastor-Flores D, Merker P, Oellerich T, Neimanis S, Schmithals C, Köberle V, Süß E, Zeuzem S, Stark H, Piiper A, Odadzic D, Schulze JO, Biondi RM.
An Allosteric Inhibitor Scaffold Targeting the PIF-Pocket of Atypical Protein Kinase C Isoforms
ACS Chem Biol. 12:564-573 (2017)

Hinrichsen I, Weßbecher IM, Huhn M, Passmann S, Zeuzem S, Plotz G, Biondi RM, Brieger A.
Phosphorylation-dependent signaling controls degradation of DNA mismatch repair protein PMS2
Mol Carcinog. 56:2663-2668 (2017)

Khageh Hosseini S, Kolterer S, Steiner M, von Manstein V, Gerlach K, Trojan J, Waidmann O, Zeuzem S, Schulze JO, Hahn S, Steinhilber D, Gatterdam V, Tampé R, Biondi RM, Proschak E, Zörnig M.
Camptothecin and its analog SN-38, the active metabolite of irinotecan, inhibit binding of the transcriptional regulator and oncoprotein FUBP1 to its DNA target sequence FUSE
Biochem Pharmacol. 146:53-62 (2017)

Parra, R.G.; Rohr, C.O.; Koile, D.; Perez-Castro, C.; Yankilevich, P.
INSECT 2.0: a web-server for genome-wide cis-regulatory modules prediction
Bioinformatics 32:1229-31 (2016)

Lavecchia, M.J.; Puig de la Bellacasa, R.; Borrell, J.I.; Cavasotto, C.N.
Investigating molecular dynamics-guided lead optimization of EGFR inhibitors
Bioorganic & Medicinal Chemistry 24:768-78 (2016)

Petracca, YL; Sartoretti, MM; Di Bella, DJ; Marin-Burgin, A; Carcagno, AL; Schinder, AF; Lanuza, GM
The late and dual origin of cerebrospinal fluid-contacting neurons in the mouse spinal cord
Development 143:880-91 (2016)

Webb AB, Lengyel IM, Jörg DJ, Valentin G, Jülicher F, Morelli LG, Oates AC
Persistence, period and precision of autonomous cellular oscillators from the zebrafish segmentation clock
eLife 5:e08438 (2016)

Inda C , dos Santos Claro P A, Bonfiglio J J , Senin SA, Maccarrone G, Turck CW, Silberstein S.
Different cAMP sources are critically involved in G protein-coupled receptor CRHR1 signaling.
J Cell Biol. 214:181-195 (2016)

Elizalde, P; Venturutti, L; Cordo Russo, R; Rivas, M; Mercogliano, M; Izzo, F; Oakley, R; Pereyra, M; De Martino, M; Proietti, C; Yankilevich, P; Roa, J; Guzmán, P; Cortese, E; Allemand, D; Huang, T; Charreau, E; Cidlowski, J; Schillaci, R.
MiR-16 mediates trastuzumab and lapatinib response in ErbB-2-positive breast and gastric cancer via its novel targets CCNJ and FUBP1
Oncogene 35:6189-6202 (2016)

Antunica-Noguerol, M., Budziñski, ML., Druker, J., Gassen, NC., Sokn, MC., Senin, S., Aprile-Garcia, F., Holsboer, F., Rein, T., Liberman, AC., Arzt, E.
The activity of the glucocorticoid receptor is regulated by SUMO conjugation to FKBP51
Cell Death Differ. 23:1579-91 (2016)

Byk LA., Iglesias NG., De Maio FA., Gebhard LG., Rossi M., Gamarnik AV.
Dengue Virus Genome Uncoating Requires Ubiquitination
MBio. 7:e00804-16 (2016)

Wu Y, Tedesco L, Lucia K, Schlitter AM, Garcia JM, Esposito I, Auernhammer CJ, Theodoropoulou M, Arzt E, Renner U, Stalla GK.
RSUME is implicated in tumorigenesis and metastasis of pancreatic neuroendocrine tumors
Oncotarget 7:57878-93 (2016)

Ferreyra Solari NE, Belforte FS, Canedo L, Videla-Richardson GA, Espinosa JM, Rossi M, Serna E, Riudavets MA, Martinetto H, Sevlever G and Perez-Castro C.
The NSL Chromatin-Modifying Complex Subunit KANSL2 Regulates Cancer Stem–like Properties in Glioblastoma That Contribute to Tumorigenesis
Cancer Research 76: 5383-5394 (2016)

Schulze JO, Saladino G, Busschots K, Neimanis S, Süß E, Odadzic D, Zeuzem S, Hindie V, Herbrand AK, Lisa MN, Alzari PM, Gervasio FL, Biondi RM.
Bidirectional Allosteric Communication between the ATP-Binding Site and the Regulatory PIF Pocket in PDK1 Protein Kinase
Cell Chemical Biology 23, 1193–1205 (2016)

Barcala Tabarrozzi AE, Andreone L, Deckers J, Castro CN, Gimeno ML, Ariolfo L, Berguer PM, Antunica Noguerol M, Liberman AC, Vettorazzi S, Tuckermann JP, De Bosscher K, Perone MJ
GR-independent down-modulation on GM-CSF bone marrow-derived dendritic cells by the selective glucocorticoid receptor modulator Compound A
Sci. Rep. 6, 36646 (2016)

Hauck S, Hiesinger K, Khageh Hosseini S, Achenbach J, Biondi RM, Proschak E, Zörnig M, Odadzic D.
Pyrazolo[1,5a]pyrimidines as a new class of FUSE binding protein 1 (FUBP1) inhibitors
Bioorg Med Chem. 24:5717-29 (2016)

Pérez-Schuster V, Kulkarni A, Nouvian M, Romano SA, Lygdas K, Jouary A, Dippopa M, Pietri T, Haudrechy M, Candat V, Boulanger-Weill J, Hakim V, Sumbre G.
Sustained Rhythmic Brain Activity Underlies Visual Motion Perception in Zebrafish
Cell Reports 17:1098–1112 (2016)

Cavasotto C., Palomba, D.
Expanding the horizons of G protein-coupled receptor structure-based ligand discovery and optimization using homology models
Chemical Communications 51:13576-94 (2015)

Gerez J, Tedesco L, Bonfiglio JJ, Fuertes M, Barontini M, Silberstein S, Wu Y, Renner U, Páez-Pereda M, Holsboer F, Stalla GK, Arzt E
RSUME inhibits VHL and regulates its tumor suppressor function
Oncogene 34: 4855-4866 (2015)

Vogl AM, Brockmann MM, Giusti SA, Maccarrone G, Vercelli CA, Bauder CA, Richter JS, Roselli F, Hafner AS, Dedic N, Wotjak CT, Vogt-Weisenhorn DM, Choquet D, Turck CW, Stein V, Deussing JM, Refojo D
Neddylation inhibition impairs spine development, destabilizes synapses and deteriorates cognition
Nat Neurosci 18:239-51 (2015)

Palomba, D., Cavasotto C.
Protein Structure Modeling in Drug Design
Chapter 8 in: In Silico Drug Discovery and Design: Theory, Methods, Challenges, and Applications. pages 215 to 245 (2015)

Rybak-Wolf A., Stottmeister C., Glazar P., Jens M., Pino N., Giusti S., Hanan M., Behm M., Bartok O., Ashwal-Fluss R., Herzog M., Schreyer L., Papavasileiou P., Ivanov A., O¨ hman M., Refojo D., Kadener S., Rajewsky N.
Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed
Molecular Cell 58, 1–16 (2015)

Pardi M.B., Ogando M.B., Schinder A.F., Marin-Burgin A.
Differential inhibition onto developing and mature granule cells generates high-frequency filters with variable gain
eLife 4:e08764 (2015)

Antico Arciuch VG, Tedesco L, Fuertes M, Arzt E
Role of RSUME in inflammation and cancer
FEBS Lett. 589:3330-5 (2015)

Páez-Pereda M, Arzt E
Function and Structure of the RWD Domain
J Biol Chem. 290:20627 (2015)

Muraro, N.I.; Ceriani, M.F.
Acetylcholine from Visual Circuits Modulates the Activity of Arousal Neurons in Drosophila
The Journal of Neuroscience 35:16315-16327 (2015)

Spyrakis, F.; Cavasotto, C.N.
Open challenges in structure-based virtual screening: Receptor modeling, target flexibility consideration and active site water molecules description
Arch. Biochem. Biophys. 583:105-19 (2015)

Sapochnik M., Nieto L., Fuertes M., Arzt E.
Molecular Mechanisms Underlying Pituitary Pathogenesis
Biochem Genet. 54:107-19 (2015)

Rodríguez TM, Saldías A, Irigo M, Velasco Zamora J, Perone MJ, Dewey RA.
Effect of TGF-ß1 stimulation on the secretome of human adipose-derived mesenchymal stromal cells
Stem Cells Transl Med. 4:894-898 (2015)

Kroon E, Schulze JO, Süß E, Camacho CJ, Biondi RM, Dömling A.
Discovery of a Potent Allosteric Kinase Modulator by Combining Computational and Synthetic Methods
Angew Chem Int Ed Engl. 16; 54:13933-6. (2015)

Pontel, L.B., Rosado, I.V., Burgos, G., Garaycoechea, J., Yu, R., Arends, M., Chandrasekaran, G., Broecker, V., Wei, W., Liu, L., Swenberg, J., Crossan, G., Patel K.J.
Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen
Mol Cell 60:177-88 (2015)

Alekseyenko OV, Chan YB, Fernandez MP, Bülow T, Pankratz MJ, Kravitz EA.
Single Serotonergic Neurons that Modulate Aggression in Drosophila
Current Biology 24:2700-7 (2014)

Giusti SA, Vercelli CA, Vogl AM, Kolarz AW, Pino NS, Deussing JM, Refojo D
Behavioral phenotyping of Nestin-Cre mice: implications for genetic mouse models of psychiatric disorders
J Psychiatr Res 55:87-95 (2014)

Luxenhofer G, Helmbrecht MS, Langhoff J, Giusti S, Refojo D, Huber AB.
MicroRNA-9 promotes the switch from early-born to late-born motor neuron populations by regulating Onecut transcription factor expression
Developmental Biology 386:358-70 (2014)

Andrews JC, Fernández MP, Yu Q, Leary GP, Leung AK, Kavanaugh MP, Kravitz EA, Certel SJ.
Octopamine neuromodulation regulates gr32a-linked aggression and courtship pathways in Drosophila males
PLoS Genet 10:e1004356 (2014)

Rossi M, Rotblat B, Ansell K, Amelio I, Caraglia M, Misso G, Bernassola F, Cavasotto CN, Knight RA, Ciechanover A, Melino G.
High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs asregulators of autophagy.
Cell Death Dis 5:e1203 (2014)

Castro CN, Barcala Tabarrozzi AE, Winnewisser J, Gimeno ML, Antunica Noguerol M, Liberman AC, Paz DA, Dewey RA, Perone MJ
Curcumin ameliorates autoimmune diabetes. Evidence in accelerated murine models of type 1 diabetes.
Clin Exp Immunol. 177:149-60 (2014)

Simerman AA, Perone MJ, Gimeno ML, Dumesic DA and Chazenbalk GD
A Mystery Unraveled: Non-tumorigenic pluripotent stem cells in human adult tissues
Expert Opinion on Biological Therapy 14:917-929 (2014)

Antunica-Noguerol, M., Aprile-Garcia, F., Budziñski, M.L., Proto-Cassina, L., Liberman, A.C., Arzt, E.
The Interplay between the Glucocorticoid Receptor Activity and post-translational Modifications in the Immune and Neuroendocrine Systems
Advances in Neuroimmune Biology 5:19-32 (2014)

Giusti SA, Vogl AM, Brockmann MM, Vercelli CA, Rein ML, Trümbach D, Wurst W, Cazalla D, Stein V, Deussing JM, Refojo D
MicroRNA-9 controls dendritic development by targeting REST
Elife 3 (2014)

Liberman, A.C., Antunica-Noguerol, M., Arzt, E.
Modulation of the glucocorticoid receptor activity by post-translational modifications
Nuclear Receptor Research 1:1-15 (2014)

Bajard L, Morelli LG, Ares S, Pecreaux J, Jülicher F, Oates AC
Wnt-regulated dynamics of positional information in zebrafish somitogenesis
Development 141, 1381–1391 (2014)

Jörg D, Morelli LG, Ares S, Jülicher F
Synchronization dynamics in the presence of coupling delays and phase shifts
Phys. Rev. Lett. 112, 174101 (2014)

Soroldoni D, Jörg DJ, Morelli LG, Richmond DL, Schindelin J, Jülicher F, Oates AC
A Doppler effect in embryonic pattern formation
Science 345, 222–225 (2014)

Uriu K, Morelli LG
Collective cell movement promotes synchronization of coupled genetic oscillators
Biophys. J. 107, 514–526 (2014)

Zhang H, Neimanis S, Lopez-Garcia LA, Arencibia JM, Amon S, Stroba A, Zeuzem S, Proschak E, Stark H, Bauer AF, Busschots K, Jørgensen TJ, Engel M, Schulze JO, Biondi RM.
Molecular Mechanism of Regulation of the Atypical Protein Kinase C by N-terminal Domains and an Allosteric Small Compound
Chem. Biol. 21:754-65 (2014)

Pontel, L.B., Scampoli, N., Porwollik, S., Checa, S., McClelland, M., Soncini F.C.
Identification of a Salmonella ancillary copper detoxification mechanism by a comparative analysis of the genome-wide transcriptional response to copper and zinc excess
Microbiology 160:1659-69. (2014)

Bonfiglio, J.J.; Inda, C.; Senin, S.; Maccarrone, G.; Refojo, D.; Giacomini, D.; Turck, C.; Holsboer, F.; Arzt, E.; Silberstein, S.
B-Raf and CRHR1 internalization mediate biphasic ERK1/2 activation by CRH in hippocampal HT22 cells
Molecular Endocrinology 27:491-510 (2013)

Jeong, Y.T.; Rossi, M.; Cermak, L.; Guijarro, M.V.; Saraf, A.; Florens, L.; Washburn, M.P.; Sung, P.; Hernando, E.; Schildkraut, C.; Pagano, M.
FBH1 mediates DNA double strand breakage and apoptosis in response to DNA replication stress.
J of Cell Biol. 200:141-9 (2013)

Rossi, M.; Duan, S.; Jeong, Y.T.; Horn, M.; Saraf, A.; Florens, L.; Washburn, M.P.; Antebi, A.; Pagano, M.
Regulation of the CRL4Cdt2 ubiquitin ligase by the SCFFbxo11 ubiquitin ligase.
Mol Cell. 49:1159-66 (2013)

Barcala Tabarrozzi, A.E.; Castro, C.N.; Dewey, R.A.; Sogayar, M.C.; Labriola, L.; Perone, M.J.
Therapeutics utilizing cell-based interventions for type 1 diabetes mellitus
Clinical & Experimental Immunology 171:135-146 (2013)

Abbas, A.; Mueller, A.; Shibata, E.; Keaton, M.; Rossi, M.; Dutta, A.
CRL1-FBXO11 promotes Cdt2 ubiquitylation and degradation and regulates Pr-Set7/Set8-mediated cellular migration.
Mol Cell. 49:1147-58 (2013)

Curic, S.; Wu, Y.; Shan, B.; Schaaf, C.; Utpadel, D.; Lange, M.; Kuhlen, D.; Perone, M.J.; Arzt, E.; Stalla, G.K.; Renner, U.
Curcumin acts anti-proliferative and pro-apoptotic in human meningiomas.
Journal of Neuro-Oncology 113:385-396 (2013)

Gerez, J.; Fuertes, M.; Tedesco, L.; Silberstein, S.; Sevlever, G.; Paez Pereda, M.; Holsboer, F.; Turjanski, A.; Arzt, E.
In silico structural and functional characterization of the RSUME splice variants
PLoS One 8:e57795 (2013)

Druker, J.; Liberman, A.C.; Antunica Noguerol, M.; Gerez, J.; Paez Pereda, M.; Rein, T.; Iñiguez Lluhí, J.A.; Holsboer, F., Arzt, E.
RSUME enhances Glucocorticoid Receptor SUMOylation and transcriptional activity
Molecular and Cellular Biology 33:2116-27 (2013)

Rohr, C.O.; Parra, R.G.;Yankilevich, P.;Perez Castro, C.
INSECT: In silico search for co-occurring transcription factors
Bioinformatics 29:2852-2858 (2013)

Antico Arciuch V.G., Russo M.A., Kang K.S., Di Cristofano A.
Inhibition of AMPK and Krebs Cycle Gene Expression Drives Metabolic Remodeling of Pten- Deficient Preneoplastic Thyroid Cells.
Cancer Res 73:5459-72 (2013)

Fernández MP, Kravitz EA.
Aggression and courtship in Drosophila: pheromonal communication and sex recognition
J Comp Physiol A Neuroethol Sens Neural Behav Physiol 199:1065-76 (2013)

Petrov RR, Knight L, Chen SR, Wager-Miller J, McDaniel SW, Diaz F, Barth F, Pan HL, Mackie K, Cavasotto CN, Diaz P.
Mastering tricyclic ring systems for desirable functional cannabinoid activity
Eur J Med Chem 69C:881-907 (2013)

Brand CS, Hocker HJ, Gorfe AA, Cavasotto CN, Dessauer CW.
Isoform selectivity of adenylyl cyclase inhibitors: characterization of known and novel compounds
J Pharmacol Exp Ther 347:265-75 (2013)

Doménech R, Hernández-Cifre JG, Bacarizo J, Díez-Peña AI, Martínez-Rodríguez S, Cavasotto CN, de la Torre JG, Cámara-Artigás A, Velázquez-Campoy A, Neira JL.
The histidine-phosphocarrier protein of the phosphoenolpyruvate: sugar phosphotransferase system of Bacillus sphaericus self-associates
PLoS One 8:e69307 (2013)

Díaz Flaqué, C.M., Galigniana, M. N., Béguelin, W., Vicario, R., Proietti, J.C., Cordo Russo, R., Rivas, A.M., Tkach, M., Guzmán, P., Roa, C. J., Maronna, E., Pineda, V., Muñoz S., Mercogliano, F.M., Charreau, H.E., Yankilevich, P., Schillaci, R., Elizalde V.P.
Progesterone receptor assembly of a transcriptional complex along with activator protein 1, signal transducer and activator of transcription 3 and ErbB-2 governs breast cancer growth and predicts response to endocrine therapy
Breast Cancer Research 15:R118 (2013)

Aprile-Garcia F, Antunica-Noguerol M, Budziñski ML, Liberman AC, Arzt E.
Novel insights into the neuroendocrine control of inflammation: the role of GR and PARP1.
Endocr Connect 3:R1-R12. doi: 10.1530/EC-13-0079 (2013)

Muraro NI, Pírez N and Ceriani MF
The Circadian system: Plasticity at many levels
Neuroscience 247C:280-293 (2013)

Driscoll H, Muraro NI and Baines RA.
Pumilio-2 regulates translation of Nav1.6 to mediate homeostasis of membrane excitability
J. Neurosci 33:9644-54 (2013)

Perez Castro, C.; Renner, U.; Haedo, M.; Gunter, K.; Stalla, G.K.; Arzt, E.
Cellular and Molecular Specificity of Pituitary Gland Physiology
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